In the homecare domain, workflows are in the mainstream for supporting the coordination and monitoring of care processes which involve managing a sequence of care workflow (careflow) activities, transmitting the information required for providing care and supporting the invocation of appropriate human and/or IT resources. However, the design of these careflows for later enactment by a Workflow Management System remains a complex task, heavily dependent on patients’ profiles and accordingly requiring to be distinctly personalised. This paper proposes an ontology-driven design approach for careflows, to facilitate the construction of personalized careflows. Following an approach grounded in Model-Driven Engineering (MDE), our methodology is based on the matching of ontologies between conceptual models of homecare and a semantic representation of Business Process Modeling Notation (BPMN) which is associated with both Actor and Case Profile ontological models.