Formulation of solid products: two-component tablets with a disintegrating agent - IMT Mines Albi-Carmaux Accéder directement au contenu
Article Dans Une Revue Polymer international Année : 2003

Formulation of solid products: two-component tablets with a disintegrating agent

Résumé

The formulation of binary tablets containing an insoluble powder and a disintegrating agent is examined from the point of view of the particle packing theory in terms of the relative size and proportion of the two components. A relationship is found between the overall porosity and the crush resistance, and between the contacts between particles and the disintegration time. Tablets made with an industrial tablet press for three different systems, caffeine-starch, cocoa-ultrafine sugar and cocoa-icing sugar, were tested for crush resistance and disintegration time. The results followed the theoretical predictions. (C) 2003 Society of Chemical Industry.
Fichier principal
Vignette du fichier
2003.S.Hutin et al**HAL.pdf (1.02 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

hal-01626711 , version 1 (23-02-2018)

Identifiants

Citer

S Hutin, Philippe Accart, Driss Oulahna, John A. Dodds. Formulation of solid products: two-component tablets with a disintegrating agent. Polymer international, 2003, 52 (4), pp.581-585. ⟨10.1002/pi.1194⟩. ⟨hal-01626711⟩
67 Consultations
64 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More