Residence time distribution of a pharmaceutical grade polymer melt in a single screw extrusion process - IMT Mines Albi-Carmaux Accéder directement au contenu
Article Dans Une Revue Chemical Engineering Research and Design Année : 2009

Residence time distribution of a pharmaceutical grade polymer melt in a single screw extrusion process

Résumé

The residence time distribution (RTD) of a flowing polymer through a single screw extruder was studied. This extruder allows injecting supercritical carbon dioxide (scCO(2)) used as physical foaming agent. The tested material is Eudragit E100, a pharmaceutical polymer. RTD was measured at various operating conditions and a model describing RTD has been developed. High screw speed or high temperature implies short residence time, but these parameters do not have the same effect on polymer flow. In the flow rate range studied, scCO(2) has no significant influence. A mathematical model consisting of a plug flow reactor in series with a continuous stirred tank reactor (CSTR) cross-flowing with a dead volume fitted well the experimental data.
Fichier principal
Vignette du fichier
2009-Nikitine-ChERD-HAL.pdf (401.2 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

hal-01618296 , version 1 (24-11-2017)

Identifiants

Citer

Clémence Nikitine, Élisabeth Rodier, Martial Sauceau, Jacques Fages. Residence time distribution of a pharmaceutical grade polymer melt in a single screw extrusion process. Chemical Engineering Research and Design, 2009, 87 (6A), p.809-816. ⟨10.1016/j.cherd.2008.10.008⟩. ⟨hal-01618296⟩
82 Consultations
958 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More